A Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems.
This text book is a guide for pharmaceutical academics (students and teachers) as well as industry professionals learning about drug delivery and formulation. Chapters presents comprehensive information about self-emulsifying formulations by providing an in-depth understanding of the basic concepts...
| Kolejni autorzy: | , |
|---|---|
| Format: | Licensed eBooks |
| Język: | angielski |
| Wydane: |
Singapore :
Bentham Science Publishers,
2021.
|
| Dostęp online: | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2962573 |
Spis treści:
- Cover
- Title
- Copyright
- End User License Agreement
- Contents
- Foreword
- Preface
- List of Contributors
- Different Methodologies for Improving Solubility and Bioavailability
- Ravinder Verma1, Deepak Kaushik1,*, Ritu Kaushik1 and Vandana Singh1
- INTRODUCTION
- DIFFICULTIES IN THE ORAL DRUG DELIVERY
- ORAL BIOAVAILABILITY
- REASON FOR POOR ORAL BIOAVAILABILITY
- DRUG SOLUBILITY
- REQUIREMENT FOR SOLUBILITY IMPROVEMENT
- APPROACHES TO ENHANCE ORAL BIOAVAILABILITY
- VARIOUS TECHNIQUES FOR IMPROVING BIOAVAILABILITY
- Salt Formation
- Cyclodextrins Based Complexes
- TECHNIQUES OF COMPLEXATION
- Kneading Technique
- Co-precipitation Technique
- Spray Drying
- NOVEL FORMULATION APPROACHES FOR BIOAVAILABILITY ENHANCEMENT
- Polymeric Micelles
- Liposomes
- Solid Lipid Nanoparticles (SLNs)
- Dendrimers
- PARTICLE SIZE REDUCTION
- Strategies
- Mechanical Micronization
- Jet Milling
- Ball Milling
- High-Pressure Homogenization
- Engineered Particle Size Control
- Strategies of Cryogenic Method
- Cryogenic Method
- Spray Freezing onto Cryogenic Fluids
- Spray Freezing into Cryogenic Liquids
- Spray Freezing into Vapor over Liquid
- Ultra-rapid Freezing (URF)
- Crystal Engineering
- Co-crystals
- Nanoparticles
- Solid Dispersion (SD)
- TECHNIQUES OF SOLID DISPERSION
- Fusion (melt) Technique
- Solvent Technique
- Dropping Technique
- Co-crystal Formation
- Supercritical Fluid Recrystallization (SCF)
- Sonocrystallisation
- Liquisolid Technique
- Formation of Inclusion Complex
- Kneading Method
- Lyophilization/Freeze-Drying Technique
- Microwave Irradiation Method
- Self-micro Emulsifying Drug Delivery Systems (SMEDDS)
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Introduction to Lipid-Based Drug Delivery Systems for Oral Delivery
- Deepak Kaushik1,*, Ravinder Verma1, Rekha Rao2 and Prerna Kaushik1
- LIPID-BASED DRUG DELIVERY SYSTEM (LBDDS)
- A Perfect Oral Lipid-Based Dosage Forms Must Meet Various Aspects
- Benefits of LBDDS
- LIPID FORMULATION CLASSIFICATION SYSTEM
- Four Types of LFCS
- Classification System for Lipid Formulations
- APPROACHES IN LBDDS
- Emulsion
- Microemulsion
- Nanoemulsion
- Liposomes
- Solid Lipid Nanoparticles
- Niosomes
- Lipospheres
- Ethosomes
- Self-emulsifying Drug Delivery System (SEDDS)
- SMEDDS AND SNEDDS
- Nano Lipid Carriers (NLCs)
- FORMULATION DEVELOPMENT AND CHARACTERIZATION
- Parameters to be Judged for the Development of the Formulation
- GUIDELINES FOR DESIGNING OF LBFS
- FORMULATION FACTORS INFLUENCING BIOAVAILABILITY OF DRUGS FROM LBDDS
- Lipid Digestion
- Mean Droplet Size of Emulsion
- Hydrophobic Nature of API
- Chemism of Lipids
- Ingredient Selection for LBFs
- ANALYSIS OF EXCIPIENTS IN LBDDS
- Chemical Analysis
- Physical Analysis
- Analysis of Physiological Effects of Ingredients
- MECHANISM OF LIPID-BASED DRUG DELIVERY SYSTEM