Neurocysticercosis : from diagnosis to treatment /

"Neurocysticercosis, a preventable parasitic infection of the central nervous system caused by tapeworm, is a serious, potentially fatal disease that can cause neurologic syndromes such as epileptic seizures. Chapter One of this monograph describes the existing treatment options for neurocystic...

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Ētahi atu kaituhi: Chavez, Mark A. (Editor)
Hōputu: Licensed eBooks
Reo:Ingarihi
I whakaputaina: New York : Nova Science Publishers, [2021]
Rangatū:Neuroscience research progress
Urunga tuihono:https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2944021
Rārangi ihirangi:
  • Intro
  • Contents
  • Preface
  • Treatment of Neurocysticercosis: Current and Future Options
  • Abstract
  • Introduction
  • Life Cycle
  • Clinical Manifestations of NCC
  • Pathology of NCC
  • Extraparenchymal NCC
  • Other forms of NCC
  • Existing Treatment
  • Symptomatic Therapy
  • Corticosteroids
  • Antiepileptic Drugs (AEDs)
  • Anti-Parasitic/Cysticidal Therapy
  • Surgery
  • Limitations of Approved Cysticidal Drugs
  • Repositioned Drugs
  • Nitazoxanide
  • Mepacrine/Quinacrine
  • Tribendimidine
  • Paromomycin
  • Tamoxifen
  • Metrifonate (Trichlorfon)
  • Potential/Novel Drug Targets
  • Protein Kinases
  • Proteases
  • Estrogen Receptor-Like Proteins
  • Insulin Receptors
  • Acetylcholinesterase's
  • G-Protein-Coupled Receptors
  • Parasite Antioxidant Enzyme
  • Plasminogen and Plasmin
  • Future Perspectives
  • References
  • The Challenge of Deciphering Certainty from Ambiguity for the Laboratory Diagnosis of Neurocysticercosis
  • 1. Introduction
  • 2. Guidelines for NCC Diagnosis
  • 3. Available Diagnostic Tools for NCC
  • 3.1. Neuroimaging Techniques (MRI and CT)
  • 3.1.1. Sero-Diagnostic Tools
  • 3.1.2. Enzyme Electro-Immune Transfer Blot
  • 3.1.3. Enzyme Linked Immunosorbent Assay (ELISA)
  • 3.1.4. Sandwich ELISA
  • 3.1.5. Direct ELISA
  • 3.1.6. Antibody ELISA
  • 3.1.7. DOT ELISA
  • 3.1.8. Molecular Assay and New Age Tools
  • 3.1.9. Polymerase Chain Reaction
  • 3.1.10. TaqMan PCR
  • 3.1.11. Quantitative PCR (qPCR)
  • 3.1.12. Multiplex PCR
  • 3.1.13. Lymphocyte Transformation Test (LTT)
  • 3.1.14. Loop Mediated Isothermal Amplification (LAMP)
  • 3.1.15. Magnetic Resonance Spectroscopy (MRS)
  • 3.1.16. miRNA
  • 3.1.17. Exosome's Detection
  • Conclusion
  • References
  • Trends in the Diagnosis of Human Neurocysticercosis: Issues and Challenges
  • Abstract
  • Introduction
  • Antibody Detection
  • Crude Soluble Extract Antigens.
  • Excretory-Secretory Antigens
  • Purified Antigenic Fractions
  • Recombinant Antigens
  • Antigen Detection
  • Urine and Saliva Samples
  • Nucleic Acid Detection
  • Polymerase Chain Reaction (PCR)
  • Loop-Mediated Isothermal Amplification (LAMP)
  • Genotype Variation in the Parasite
  • Proteomics
  • Cell Mediated Techniques
  • Clinical Considerations
  • Presentation vs. Diagnosis
  • Single vs. Multiple Lesions
  • Childhood NCC
  • Post-Treatment Follow-Up
  • Conclusion
  • References
  • Index
  • Blank Page.