Neurocysticercosis : from diagnosis to treatment /
"Neurocysticercosis, a preventable parasitic infection of the central nervous system caused by tapeworm, is a serious, potentially fatal disease that can cause neurologic syndromes such as epileptic seizures. Chapter One of this monograph describes the existing treatment options for neurocystic...
| Muut tekijät: | |
|---|---|
| Aineistotyyppi: | Licensed eBooks |
| Kieli: | englanti |
| Julkaistu: |
New York :
Nova Science Publishers,
[2021]
|
| Sarja: | Neuroscience research progress
|
| Linkit: | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2944021 |
Sisällysluettelo:
- Intro
- Contents
- Preface
- Treatment of Neurocysticercosis: Current and Future Options
- Abstract
- Introduction
- Life Cycle
- Clinical Manifestations of NCC
- Pathology of NCC
- Extraparenchymal NCC
- Other forms of NCC
- Existing Treatment
- Symptomatic Therapy
- Corticosteroids
- Antiepileptic Drugs (AEDs)
- Anti-Parasitic/Cysticidal Therapy
- Surgery
- Limitations of Approved Cysticidal Drugs
- Repositioned Drugs
- Nitazoxanide
- Mepacrine/Quinacrine
- Tribendimidine
- Paromomycin
- Tamoxifen
- Metrifonate (Trichlorfon)
- Potential/Novel Drug Targets
- Protein Kinases
- Proteases
- Estrogen Receptor-Like Proteins
- Insulin Receptors
- Acetylcholinesterase's
- G-Protein-Coupled Receptors
- Parasite Antioxidant Enzyme
- Plasminogen and Plasmin
- Future Perspectives
- References
- The Challenge of Deciphering Certainty from Ambiguity for the Laboratory Diagnosis of Neurocysticercosis
- 1. Introduction
- 2. Guidelines for NCC Diagnosis
- 3. Available Diagnostic Tools for NCC
- 3.1. Neuroimaging Techniques (MRI and CT)
- 3.1.1. Sero-Diagnostic Tools
- 3.1.2. Enzyme Electro-Immune Transfer Blot
- 3.1.3. Enzyme Linked Immunosorbent Assay (ELISA)
- 3.1.4. Sandwich ELISA
- 3.1.5. Direct ELISA
- 3.1.6. Antibody ELISA
- 3.1.7. DOT ELISA
- 3.1.8. Molecular Assay and New Age Tools
- 3.1.9. Polymerase Chain Reaction
- 3.1.10. TaqMan PCR
- 3.1.11. Quantitative PCR (qPCR)
- 3.1.12. Multiplex PCR
- 3.1.13. Lymphocyte Transformation Test (LTT)
- 3.1.14. Loop Mediated Isothermal Amplification (LAMP)
- 3.1.15. Magnetic Resonance Spectroscopy (MRS)
- 3.1.16. miRNA
- 3.1.17. Exosome's Detection
- Conclusion
- References
- Trends in the Diagnosis of Human Neurocysticercosis: Issues and Challenges
- Abstract
- Introduction
- Antibody Detection
- Crude Soluble Extract Antigens.
- Excretory-Secretory Antigens
- Purified Antigenic Fractions
- Recombinant Antigens
- Antigen Detection
- Urine and Saliva Samples
- Nucleic Acid Detection
- Polymerase Chain Reaction (PCR)
- Loop-Mediated Isothermal Amplification (LAMP)
- Genotype Variation in the Parasite
- Proteomics
- Cell Mediated Techniques
- Clinical Considerations
- Presentation vs. Diagnosis
- Single vs. Multiple Lesions
- Childhood NCC
- Post-Treatment Follow-Up
- Conclusion
- References
- Index
- Blank Page.