Exosomes : biogenesis, therapeutic applications and emerging research /
| その他の著者: | |
|---|---|
| フォーマット: | Licensed eBooks |
| 言語: | 英語 |
| 出版事項: |
New York :
Nova Biomedical,
[2016]
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| シリーズ: | Cell biology research progress.
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| オンライン･アクセス: | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1385349 |
目次:
- Preface; Chapter 1; Molecular Mechanisms of Exosome Biogenesis; Abstract; Introduction; 1. Origin of Exosomes; 2. Exosome Biogenesis: Membrane Bending and Cargo Recruitment; The ESCRT Machinery; ESCRT-Dependent Mechanisms of Exosome Biogenesis; ESCRT-Independent Mechanisms of Exosome Biogenesis; Ceramide; Lysobisphosphatidic Acid (LBPA); Tetraspanins; 3. Exosome Release; Is Exosome Release Signal Dependent?; Rab GTPases Regulate Exosomes Release; The Role of Cytoskeleton and SNAREs in Exosome Release; 4. The Diversity of MVBs; Conclusion; References; Chapter 2.
- Phenotyping of Small Extracellular Vesicles from Clinically Important Body Fluids Using Protein MicroarrayAbstract; Introduction; Material and Methods; Sampling; Printing of Protein Microarrays; EV Array Analysis; Data Analysis; Results and Discussion; Acknowledgments; References; Chapter 3; Exosomes: Mediators of Cell-Cell Communication and Potential Biomarkers in Cancer; Abstract; Introduction; 1. Exosome Biogenesis; 2. Exosomes in Cancer; 2.1. Oncogenic Transformation and Tumor Formation; 2.2. Angiogenesis; 2.3. Niche Formation and Metastasis; 2.4. Immune Evasion.
- 2.5. Chemotherapy Evasion3. Therapeutic Use; 4. Exosomes as Biomarkers; Conclusion; References; Chapter 4; Extracellular Vesicles in the Reproductive Tracts: Roles in Sperm Maturation and Function; Abstract; Introduction; Extracellular Vesicles, Characterization, Biogenesis and Impact; Conclusion; Acknowledgments; References; Index.