Health implications of perchlorate ingestion /

Perchlorate a powerful oxidant used in solid rocket fuels by the military and aerospace industry has been detected in public drinking water supplies of over 11 million people at concentrations of at least 4 parts per billion (ppb). High doses of perchlorate can decrease thyroid hormone production by...

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Bibliographic Details
Corporate Author: National Research Council (U.S.). Division of Earth Sciences
Format: Licensed eBooks
Language:English
Published: Washington, D.C. : National Academies Press, ©2005.
Online Access:https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=131245
Table of Contents:
  • Summary
  • 1. Introduction
  • 2. The thyroid and disruption of thyroid function in humans
  • 3. Epidemiologic studies of occupational and environmental exposures to perchlorate
  • 4. Animal studies
  • 5. Risk characterization of perchlorate
  • 6. Research recommendations
  • Appendix A. Biographic information on the Committee to Assess the Health Implications of Perchlorate Ingestion
  • Appendix B. Glossary
  • Appendix C. Participants at public sessions
  • Appendix D. Sensitivity of perchlorate-induced iodide uptake inhibition to serum iodide concentrations
  • Appendix E. Physiologically based pharmacokinetic modeling.