A Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems.

This text book is a guide for pharmaceutical academics (students and teachers) as well as industry professionals learning about drug delivery and formulation. Chapters presents comprehensive information about self-emulsifying formulations by providing an in-depth understanding of the basic concepts...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Այլ հեղինակներ: Kaushik, Deepak, Verma, Ravinder
Ձևաչափ: Licensed eBooks
Լեզու:անգլերեն
Հրապարակվել է: Singapore : Bentham Science Publishers, 2021.
Առցանց հասանելիություն:https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2962573
Բովանդակություն:
  • Cover
  • Title
  • Copyright
  • End User License Agreement
  • Contents
  • Foreword
  • Preface
  • List of Contributors
  • Different Methodologies for Improving Solubility and Bioavailability
  • Ravinder Verma1, Deepak Kaushik1,*, Ritu Kaushik1 and Vandana Singh1
  • INTRODUCTION
  • DIFFICULTIES IN THE ORAL DRUG DELIVERY
  • ORAL BIOAVAILABILITY
  • REASON FOR POOR ORAL BIOAVAILABILITY
  • DRUG SOLUBILITY
  • REQUIREMENT FOR SOLUBILITY IMPROVEMENT
  • APPROACHES TO ENHANCE ORAL BIOAVAILABILITY
  • VARIOUS TECHNIQUES FOR IMPROVING BIOAVAILABILITY
  • Salt Formation
  • Cyclodextrins Based Complexes
  • TECHNIQUES OF COMPLEXATION
  • Kneading Technique
  • Co-precipitation Technique
  • Spray Drying
  • NOVEL FORMULATION APPROACHES FOR BIOAVAILABILITY ENHANCEMENT
  • Polymeric Micelles
  • Liposomes
  • Solid Lipid Nanoparticles (SLNs)
  • Dendrimers
  • PARTICLE SIZE REDUCTION
  • Strategies
  • Mechanical Micronization
  • Jet Milling
  • Ball Milling
  • High-Pressure Homogenization
  • Engineered Particle Size Control
  • Strategies of Cryogenic Method
  • Cryogenic Method
  • Spray Freezing onto Cryogenic Fluids
  • Spray Freezing into Cryogenic Liquids
  • Spray Freezing into Vapor over Liquid
  • Ultra-rapid Freezing (URF)
  • Crystal Engineering
  • Co-crystals
  • Nanoparticles
  • Solid Dispersion (SD)
  • TECHNIQUES OF SOLID DISPERSION
  • Fusion (melt) Technique
  • Solvent Technique
  • Dropping Technique
  • Co-crystal Formation
  • Supercritical Fluid Recrystallization (SCF)
  • Sonocrystallisation
  • Liquisolid Technique
  • Formation of Inclusion Complex
  • Kneading Method
  • Lyophilization/Freeze-Drying Technique
  • Microwave Irradiation Method
  • Self-micro Emulsifying Drug Delivery Systems (SMEDDS)
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Introduction to Lipid-Based Drug Delivery Systems for Oral Delivery
  • Deepak Kaushik1,*, Ravinder Verma1, Rekha Rao2 and Prerna Kaushik1
  • LIPID-BASED DRUG DELIVERY SYSTEM (LBDDS)
  • A Perfect Oral Lipid-Based Dosage Forms Must Meet Various Aspects
  • Benefits of LBDDS
  • LIPID FORMULATION CLASSIFICATION SYSTEM
  • Four Types of LFCS
  • Classification System for Lipid Formulations
  • APPROACHES IN LBDDS
  • Emulsion
  • Microemulsion
  • Nanoemulsion
  • Liposomes
  • Solid Lipid Nanoparticles
  • Niosomes
  • Lipospheres
  • Ethosomes
  • Self-emulsifying Drug Delivery System (SEDDS)
  • SMEDDS AND SNEDDS
  • Nano Lipid Carriers (NLCs)
  • FORMULATION DEVELOPMENT AND CHARACTERIZATION
  • Parameters to be Judged for the Development of the Formulation
  • GUIDELINES FOR DESIGNING OF LBFS
  • FORMULATION FACTORS INFLUENCING BIOAVAILABILITY OF DRUGS FROM LBDDS
  • Lipid Digestion
  • Mean Droplet Size of Emulsion
  • Hydrophobic Nature of API
  • Chemism of Lipids
  • Ingredient Selection for LBFs
  • ANALYSIS OF EXCIPIENTS IN LBDDS
  • Chemical Analysis
  • Physical Analysis
  • Analysis of Physiological Effects of Ingredients
  • MECHANISM OF LIPID-BASED DRUG DELIVERY SYSTEM

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