DNA microarrays and gene expression : from experiments to data analysis and modeling /
DNA microarrays are revolutionizing biology and medicine. They can provide a snapshot of the level of gene expression in a cell and are therefore a powerful tool with which to study biological phenomena at the molecular level. This inter-disciplinary introduction will be essential reading for resear...
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| Natura: | Licensed eBooks |
| Lingua: | inglese |
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Cambridge, U.K. ; New York :
Cambridge University Press,
2002.
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| Accesso online: | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=120542 |
Sommario:
- Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction, clustering, and regulatory regions; 7 The design, analysis, and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index.