TY  - GEN
T1  - Nuclear receptors : a practical approach
T2  - Practical approach series ;
A2  - Picard, Didier
LA  - English
PP  - New York
PB  - Oxford University Press
YR  - 1999
UL  - https://ebooks.jgu.edu.in/Record/ebsco_acadsubs_ocm53980104
AB  - The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new.
OP  - 285
CN  - QP572.S7 S757 1999eb
SN  - 0585483728
SN  - 9780585483726
SN  - 1280375698
SN  - 9781280375699
SN  - 0199637431
SN  - 0199637423
KW  - Steroid hormones : Receptors.
KW  - Nuclear receptors (Biochemistry)
KW  - Transcription factors.
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Transcription Factors
KW  - Receptors, Steroid
KW  - Hormones stéroïdes : Récepteurs.
KW  - Récepteurs nucléaires (Biochimie)
KW  - Facteurs de transcription.
KW  - SOCIAL SCIENCE : Anthropology : Physical.
KW  - Receptors, Cytoplasmic and Nuclear.
KW  - Receptors, Steroid.
KW  - Steroid hormones : Receptors
KW  - Transcription factors
KW  - Biochimie.
KW  - Hormones stéroides : Récepteurs.
KW  - Laboratory Manual
KW  - Laboratory manuals
KW  - Laboratory manuals.
KW  - Manuels de laboratoire.
ER  -