TY - GEN T1 - Rethinking homeostasis : allostatic regulation in physiology and pathophysiology T2 - Bradford Bks. A1 - Schulkin, Jay LA - English PP - Cambridge, Mass. PB - MIT Press YR - 2003 UL - https://ebooks.jgu.edu.in/Record/ebsco_acadsubs_ocm52289168 AB - Homeostasis, a key concept in biology, refers to the tendency toward stability in the various bodily states that make up the internal environment. Examples include temperature regulation and oxygen consumption. The body's needs, however, do not remain constant. When an organism is under stress, the central nervous system works with the endocrine system to use resources to maintain the overall viability of the organism. The process accelerates the various systems' defenses of bodily viability, but can violate short-term homeostasis. This allostatic regulation highlights our ability to anticipate, adapt to, and cope with impending future events. In Rethinking Homeostasis, Jay Schulkin defines and explores many aspects of allostasis, including the wear and tear on tissues and accelerated pathophysiology caused by allostatic overload. Focusing on the concept of motivation and its relationship to the central nervous system function and specific hormonal systems, he applies a neuroendocrine perspective to central motive states such as cravings for water, sodium, food, sex, and drugs. He examines in detail the bodily consequences of the behavioral and neuroendocrine regulation of fear and adversity, the endocrine regulation of normal and preterm birth, and the effects of drug addiction on the body. Schulkin's presentation of allostasis lays the foundation for further study. OP - 296 NO - "A Bradford book." CN - QP90.4 .S38 2003eb SN - 9780262283274 SN - 0262283271 SN - 0585446601 SN - 9780585446608 SN - 9780262194808 SN - 0262194805 SN - 0262293587 SN - 9780262293587 KW - Homeostasis. KW - Neuroendocrinology. KW - Psychophysiology. KW - Biological control systems. KW - Homeostasis KW - Neuroendocrinology KW - Neurosecretory Systems : physiology KW - Psychophysiology KW - Homéostasie. KW - Neuroendocrinologie. KW - Psychophysiologie. KW - Régulation (Biologie) KW - MEDICAL : Physiology. KW - SCIENCE : Life Sciences : Human Anatomy & Physiology. KW - Biological control systems KW - Homeostase. KW - Fysiologie. KW - Regelmechanismen. KW - NEUROSCIENCE/General ER -