Monoclonal antibody production - National Research Council (U.S.) (Washington, D.C. : National Academy Press, 1999)
Generation of hybridomas: permanent cell lines secreting monoclonal antibody -- In vitro production of monoclonal antibody -- Scientific needs for mouse ascites production of mAb -- Summary of advantages and disadvantages of in vitro and in vivo methods -- Large-scale production of monoclonal antibodies -- Animal-welfare issues related to the ascites method for producing monoclonal antibodies -- Conclusions and recommendations.
Includes bibliographical references.
Print version record.
eBooks on EBSCOhost
Keywords: Hybridomas; Mice as laboratory animals; Monoclonal antibodies; Antibodies, Monoclonal; Hybridomas; Hybridomes; Souris (Animal de laboratoire); Anticorps monoclonaux; HISTORY -- General; Monoclonal antibodies; Hybridomas; Mice as laboratory animals