TY - GEN T1 - Recent Advances in Biocatalysis and Metabolic Engineering for Biomanufacturing A1 - Lee, Eun Yeol LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2021 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-57721 AB - The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and chemo-, regio-, and stereo-selectivity of enzymes can be enhanced and modulated using protein engineering. Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. The aim of this book is to cover the recent advances in biocatalysis and metabolic engineering for biomanufacturing of biofuels, chemicals, biomaterials, and pharmaceuticals. Reviews and original research articles on the development of new strategies to improve the catalytic efficiency of enzymes, biosynthetic capability of cell factories, and their applications in production of various bioproducts and chemicals are included. SN - 9783039215751 SN - 9783039215744 KW - TP248.13-248.65 KW - T1-995 KW - n/a KW - fluorescein diacetate KW - Methylosinus sporium strain 5 KW - soluble methane monooxygenase KW - tunable expression system KW - FTIR spectroscopy KW - mevalonate kinase 1 KW - poly(ethylene glycol) KW - tetraethylene glycol KW - review KW - mevalonate (MVA) KW - biofilm KW - 5-hydroxymethylfurfural KW - polymer functionalization KW - microbial production KW - microbial cell factory KW - bio-hydrogen KW - redox enzymes KW - specific recognition KW - fed-batch fermentation KW - monoterpene KW - Vitreoscilla KW - Pvgb KW - bioreactor KW - 3-hydroxypropionic acid KW - cascade reactions KW - synthetic biology KW - aerobic methane bioconversion KW - starch hydrolysis KW - CYP153A KW - MEP pathway KW - cross-linked enzyme aggregate KW - interfacial activation KW - expression vectors KW - Combi-CLEAs KW - polyethyleneimine KW - bovine serum albumin KW - polyurethane foam KW - 12-hydroxydodecanoic acid KW - MEV pathway KW - amyloglucosidase KW - total enzymatic activity KW - Nylon 12 KW - biocatalytic reaction KW - Myceliophthora KW - whole-cell biotransformation KW - magnetic nanoparticles KW - lipase immobilization KW - Methanosarcina mazei KW - biocatalysis KW - acetate KW - vgb KW - C–H activation KW - artificial self-sufficient P450 KW - whole cell KW - bioplastics KW - Corynebacterium glutamicum KW - chemicals addition KW - enzyme modulation KW - Eversa KW - enzyme stabilization KW - biocatalysts KW - prokaryotic microbial factory KW - synthetic metabolic pathways KW - mannose KW - immobilization KW - (?)-?-bisabolol KW - hydrogenase KW - O2 activation KW - string film reactor KW - fatty acid synthesis KW - ?-aminododecanoic acid KW - transesterification KW - mass transfer performance KW - dodecanoic acid KW - metabolic engineering KW - glyoxal oxidase KW - small molecules KW - Candida antarctica Lipase B KW - thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology ER -