TY  - GEN
T1  - Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination
A1  - Alix-Panabieres, Catherine
LA  - eng
PB  - MDPI - Multidisciplinary Digital Publishing Institute
YR  - 2021
UL  - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-43261
AB  - The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization; their analysis at the single-cell level; their journey as CTC microemboli; their clinical relevance; their biology with the epithelial-to-mesenchymal transition (EMT); their stem-cell properties; their potential to initiate metastasis at distant sites; their ex vivo expansion; and their escape from the immune system.
SN  - 9783039286997
SN  - 9783039286980
KW  - R5-920
KW  - n/a
KW  - FOLFIRINOX
KW  - immunofluorescence imaging
KW  - AR-V7
KW  - circulating tumour cells
KW  - chemoradioresistance
KW  - CTC-based treatment decisions
KW  - rVAR2
KW  - immunophenotyping
KW  - immune system
KW  - CellSearch®
KW  - flow cytometry
KW  - clinical trials
KW  - circulating tumor DNA
KW  - synaptophysin
KW  - stem cells
KW  - colorectal cancer
KW  - melanoma
KW  - CTC biology
KW  - platelets
KW  - AR
KW  - CTC capture technology
KW  - castration resistant prostate cancer (CRPC)
KW  - PD-L1 expression
KW  - rovalpituzumab tesirine
KW  - HMB-45
KW  - thymidylate synthase
KW  - ctDNA
KW  - tumor cell dissemination
KW  - solid cancers
KW  - metastasis
KW  - locally advanced rectal cancer
KW  - miRNA
KW  - epithelial-to-mesenchymal transition (EMT)
KW  - NSCLC
KW  - tumor biomarkers
KW  - tumor stem cells
KW  - circulating tumor cells
KW  - major histocompatibility complex class I (MHCI)
KW  - bone marrow
KW  - heterogeneity
KW  - cerebrospinal liquid biopsy
KW  - fish
KW  - glioma
KW  - in vivo flow cytometry
KW  - colorectal surgery
KW  - CellSearch
KW  - single-cell analysis
KW  - disseminated tumor cells
KW  - EasyCount slides
KW  - microsatellite instability
KW  - circulating plasma cells
KW  - circulating leukemia cells
KW  - ARV7
KW  - SLUG
KW  - androgen receptor
KW  - metastatic colorectal cancer
KW  - leukocyte-derived extracellular vesicles
KW  - prostate cancer (PCa)
KW  - neutrophils
KW  - liquid biopsy
KW  - enzalutamide
KW  - CD133
KW  - enrichment and detection technologies
KW  - biomarkers
KW  - immune checkpoint inhibitors
KW  - biomarker
KW  - RAD23B
KW  - microbiome
KW  - integrin B1
KW  - ACCEPT
KW  - emboli
KW  - small-cell lung carcinoma
KW  - EPISPOT
KW  - microfluidics
KW  - early breast cancer
KW  - circulating tumor cells (CTC)
KW  - tumor-initiating cells (TICs)
KW  - immunomodulation
KW  - xenograft models
KW  - CTC-derived xenografts
KW  - malaria
KW  - circulating tumor cells (CTCs)
KW  - clinical utility
KW  - exosomes
KW  - liquid surgery
KW  - ctRNA
KW  - CTCs
KW  - epithelial–mesenchymal transition
KW  - targeted therapy
KW  - hematological cells
KW  - gene expression analysis
KW  - hepatocellular carcinoma (HCC)
KW  - breast cancer
KW  - EpCAM enrichment
KW  - prostate cancer
KW  - CTC
KW  - abiraterone
KW  - fibronectin
KW  - CTC-derived ex vivo models
KW  - CTMat
KW  - chromogranin A
KW  - CTM
KW  - exosome
KW  - thema EDItEUR::M Medicine and Nursing
ER  -