TY - GEN T1 - Design of Polymeric Hydrogels Biomaterials A2 - Silva, Diana LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2025 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-152811 AB - Hydrogels have become one of the most promising biomaterials in recent years due to their biocompatibility, versatility, and ability to mimic biological tissues and are already widely used in areas such as ophthalmology, cardiovascular health, wound healing, and regenerative medicine. These materials can be produced in the form of films, 3D-printed structures, fibers, or nanoparticles and tailored to serve as platforms for the sustained delivery of drugs and/or other bioactive molecules. Some more advanced hydrogels exhibit smart stimuli-responsive behaviors, offer self-healing capacity, or shape memory properties. Despite significant progress, challenges remain in designing new hydrogels that are both safe and high-performing. This reprint gathers some of the most recent achievements related to the synthesis, characterization, and application of the new generation of hydrogels, covering issues from the use of artificial intelligence (AI) for hydrogel development to their most innovative uses. SN - 9783725822348 SN - 9783725822331 KW - mucoadhesion KW - drug release KW - bladder tumor KW - polymeric hydrogels KW - intravesical therapy KW - polyglycerols KW - dendrimers KW - hydrogels KW - paclitaxel KW - release KW - solubilization KW - FTIR imaging KW - hydrotrope KW - modified lignocellulose KW - pentoxifylline KW - nanoparticles KW - rat model KW - wound dressing KW - injectable hydrogel nanocomposites KW - biomedical applications KW - controlled release KW - tissue engineering KW - therapeutic outcomes KW - carboxymethyl chitosan KW - microgel KW - sustained drug delivery KW - antibiotic KW - Fe (II) chelating activity KW - vancomycin KW - prolonged antibacterial effect KW - microneedles KW - drug delivery KW - dissolving microneedles KW - swelling microneedles KW - hydrogel-forming microneedles KW - microneedle manufacturing KW - hydrogel design KW - artificial intelligence KW - machine learning KW - sodium alginate KW - PNIPAM KW - 3D printing KW - MC3T3-E1 KW - bone tissue engineering KW - anti-aging KW - nanoemulgels KW - nanoemulsions KW - neuropathy KW - skin cancer KW - skin infection KW - skin inflammation KW - topical administration KW - transdermal administration KW - wound healing KW - multi-layered hydrogel KW - interfacial layer KW - self-folding KW - soft hydrogel actuators KW - hyaluronic acid KW - carboxymethyl cellulose KW - BDDE KW - fillers KW - n/a KW - thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBD Medical profession::MBDC Medical ethics and professional conduct ER -