TY - GEN T1 - Antimicrobial Biomaterials: Recent Progress A2 - Felgueiras, Helena LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2024 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-143791 AB - Biomaterials can be used as implantable devices or drug delivery platforms with a significant influence on a patients’ quality of life. Indeed, every year a substantial number of new biomaterials and scaffolding systems are engineered and introduced in the biomedical field with increased potential for biomedical uses. However, their long-term use can be threatened by the adhesion and proliferation of microorganisms, which can interact and form biofilms, or the formation of fibrosis, with cytotoxic responses being very common. Pathogenic microorganisms may cause local infection and consequent implant failure; furthermore, they can hinder the delivery of therapeutic molecules by specialized delivery platforms, turning them ineffective. Many alternatives have been proposed over the years to prevent such events, including the use of antiseptics and antibiotics or the physical modification of the biomaterial surface, with the incorporation of biomolecules of interest. From specialized polymers and functional groups to silver and, more recently, antimicrobial peptides and natural extracts, different functionalization/modification techniques have been employed in this fight against pathogenic agents. SN - 9783725816606 SN - 9783725816590 KW - soy protein isolate KW - quaternization KW - antibacterial property KW - wound healing KW - antimicrobial therapy KW - antimicrobial resistance KW - drug delivery systems KW - antimicrobials delivery KW - nanocarriers KW - antibacterial nanoformulations KW - antifungal nanoformulations KW - antiviral nanoformulations KW - antiparasitic nanoformulations KW - chitosan nanoparticles KW - yellow everzol textile dyes KW - biocompatibility KW - HaCat cells KW - antimicrobial activity KW - skin pathogens KW - cell infection assays KW - multidrug resistance KW - nanoparticles KW - antibiotic combinations KW - infectious disease KW - chitosan KW - fruit quality parameters KW - sweet orange essential oil KW - phosphoric acid KW - preharvest treatments KW - Ag@AgCl nanoparticles KW - synthesis mechanisms KW - Shewanella sp. KW - dye reduction KW - antibacterial activity KW - CO2 laser KW - Enterococcus faecalis KW - erbium laser KW - oral pathogens KW - Streptococcus mutans KW - Streptococcus sanguinis KW - drug resistance KW - molecular diagnosis KW - anti-tuberculosis therapy KW - Real-Time PCR KW - isoniazid KW - rifampicin KW - genomic DNA KW - mutation KW - vitreous enamel KW - antimicrobial coatings KW - silver KW - fungicidal activity KW - antimicrobial KW - antimycobacterial KW - benzoxaborole KW - cytotoxicity KW - molecular docking KW - multidrug-resistant tuberculosis KW - tuberculosis KW - 1H-benzo[d]imidazole derivatives KW - structure–activity relationship KW - X-ray KW - ADME KW - crossing the blood–brain barrier KW - cellobiose dehydrogenase KW - immobilization KW - antioxidant KW - cytotoxic KW - external ventricular drain KW - biofilm KW - bacteria KW - silver nanoparticles KW - antibiotics impregnated KW - biomaterial KW - porous silica spheres KW - porosity KW - surface area KW - microbial activity KW - enzyme activity KW - antibiotic resistance KW - click chemistry KW - photopolymerization KW - AMP-releasing KW - self-assembling KW - hydrogel KW - antimicrobial peptide KW - orthodontic brackets KW - S-Nitroso-N-Acetylpenicillamine (SNAP) KW - orthodontic ligatures KW - dental plaque KW - antibacterial chains KW - elastomeric chainswhite spot lesions KW - nitric oxide KW - SNAP KW - n/a KW - thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine ER -