TY - GEN T1 - Molecular Mechanism in Epithelial-Mesenchymal Transition (EMT) and Fibrosis A2 - Lisi, Sabrina LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2024 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-137817 AB - This Special Issue of the International Journal of Molecular Sciences (IJMS), entitled “Molecular Mechanism in Epithelial-Mesenchymal Transition (EMT) and Fibrosis”, collected 15 original research papers (5 reviews and 10 articles) written by a panel of experts from different countries who highlight recent advances in the EMT process.Navigating the complex field of EMT, this Special Issue introduces the current understanding of the underlying mechanisms of EMT in the evolution and progression of fibrogenesis and discusses potential strategies for attenuating EMT to prevent and/or inhibit fibrosis.Overall, the 15 scientific articles in this Special Issue of the International Journal of Molecular Sciences provide valuable insights into the complex mechanisms governing the EMT process linked to fibrosis and have highlighted the potential of novel therapeutic strategies. In the last few years, the field of EMT has shown considerable promise, and there is still much to be learned. As our understanding continues to grow, we hope that this Special Issue serves as a catalyst for further research and innovation in this developing field. SN - 9783725807024 SN - 9783725807017 KW - defense peptides KW - immune peptides KW - pulmonary fibrosis KW - hypersensitivity pneumonitis KW - extrinsic allergic alveolitis KW - autoimmune thyroid diseases KW - Graves’ disease KW - Hashimoto’s Thyroiditis KW - TGF-β KW - EMT KW - primary cilia KW - mesenchymal stem cells KW - mechanotransduction KW - collagen KW - oxidation KW - YAP/TAZ KW - focal adhesion KW - proliferative vitreoretinal diseases (PVDs) KW - experimental models KW - epithelial-mesenchymal transition (EMT) KW - preeclampsia KW - placenta KW - decidua KW - MET KW - 15-PGDH KW - PGT KW - signal transducer and activator of transcription 3 (STAT3) KW - glaucoma filtration surgery KW - fibrosis KW - suppressor of cytokine signaling 3 (SOCS3) KW - epithelial-to-mesenchymal transition KW - chronic airway diseases KW - remodelling KW - collagen 1a1 KW - bleomycin KW - lansoprazole KW - Mcp1 KW - Mcp3 KW - Opn KW - idiopathic pulmonary fibrosis KW - surfactant related gene mutation KW - telomere related gene mutation KW - SFTPC KW - SFTPA2 KW - RTEL1 KW - TERT KW - lung tissue KW - RNA expression KW - corylin KW - anti-inflammation KW - liver fibrosis KW - hepatic stellate cell KW - growth arrest-specific gene 6/AXL signaling pathway KW - inflammation KW - pulmonary malignancy KW - natural products KW - aggressiveness KW - tumor stem cells KW - mechanism of action KW - fibroblast KW - bioinformatics KW - heterogeneity KW - predictive model KW - asthma KW - airway KW - epithelial to mesenchymal transition KW - Cl− channel KW - cell volume KW - epigenetic KW - DNA methylation KW - histone modification KW - ncRNA KW - STAT4 KW - STAT1 KW - cytokine regulation KW - interferons KW - EGF KW - n/a ER -