TY - GEN T1 - Human Biomonitoring in Health Risk Assessment A2 - Rousselle, Christophe LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2023 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-100018 AB - Europe’s zero-pollution agenda should depart from an understanding of how the European citizens’ bodies are polluted by synthetic chemicals and prioritize the reduction of the chemical body burden and associated health impacts. In this context, Human Biomonitoring (HBM) is an important and valuable tool for assessing the internal exposure of humans resulting from aggregated exposure to chemicals. Though many obstacles still hinder the use of HBM data, the growing availability of HBM data offers an opportunity for improving and refining Human Risk Assessment. This Special Issue intends to illustrate, using case studies, how HBM data could be used to better estimate internal exposure and resulting risks. Case studies on exposure from consumer products (cosmetic products, non-food products, etc.) or exposures via food or water in the general population or among workers contributed to better identifying the obstacles hindering a broader use of HBM data in RA. A better understanding of population exposure and the exposure of vulnerable groups against health-based human biomonitoring guidance values also provides the basis for effective risk management to reduce impacts on health. I would like to thank all the authors for submitting their original contributions to this Special Issue. We greatly appreciate the support of all the reviewers who spent time evaluating and improving the quality of the manuscripts. I would also like to thank the editors of Toxics for their kind invitation and Selena Li of the Toxics Editorial Office for her invaluable support. SN - 9783036570044 SN - 9783036570051 KW - biomonitoring KW - nanoparticles KW - lung diseases KW - mineralogical analysis of broncho-alveolar lavages KW - occupational exposure KW - human biomonitoring KW - UV filters KW - benzophenone-3 KW - HBM4EU KW - risk assessment KW - RCR KW - margin of safety KW - oxidative stress KW - MDA KW - systematic review KW - meta-analysis KW - urinary biomarker KW - reference range KW - general population KW - pesticides KW - exposure KW - operators KW - workers KW - residents KW - bystanders KW - tree-grown produce KW - fruits KW - vine KW - systemic exposure KW - paints production KW - TiO2 powders KW - biological monitoring KW - exhaled breath condensate KW - occupational health KW - ortho-toluidine KW - urinary mass-balance KW - PBPK modelling KW - human biomonitoring (HBM) KW - internal exposure KW - biomarkers KW - endocrine disruptors KW - bisphenol A (BPA) KW - bisphenol S (BPS) KW - bisphenols KW - human biomonitoring guidance value (HBM-GV) KW - physiologically based pharmacokinetic modelling (PBPK) KW - organophosphorus flame retardants KW - dietary exposure KW - children KW - malondialdehyde KW - reference values KW - benzene KW - COVID-19 pandemic KW - lockdown KW - Rome KW - elements KW - urban traffic KW - metabolomics KW - dimethylformamide KW - DMF KW - HBM-GV KW - guidance value KW - biomarker KW - toxicokinetics KW - health effects KW - liver KW - carcinogenicity KW - reprotoxic effects KW - chlorpyrifos KW - pesticide exposure KW - pesticide risk assessment KW - mercury KW - methylmercury KW - European Human Biomonitoring Initiative (HBM4EU) KW - co-exposure KW - workplace KW - mixture risk assessment (MRA) KW - adipose tissue KW - meta-regression KW - partition coefficients KW - persistent organic pollutants KW - n/a KW - thema EDItEUR::M Medicine and Nursing KW - thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology ER -