TY - GEN T1 - Genetic Complexity of Hormone Sensitive Cancers A2 - Batra, Jyotsna LA - eng PB - MDPI - Multidisciplinary Digital Publishing Institute YR - 2023 UL - https://ebooks.jgu.edu.in/Record/doab-20.500.12854-100001 AB - In this Special Issue, authors from nine countries on five continents provide overviews on and insights into current research topics related to the ‘Genetic Complexity of Hormone-Sensitive Cancers’. The chapters cover topics on completely novel technologies and instruments revolutionizing our view of biological entities, and also, novel extensions and revisions of existing and well-established technologies such as genetic probes and bar-coding techniques, which add a new dimension to microscopy, as they allow us to visualize DNA sequences and mRNA in situ. With this Special Issue, the editors wanted to create a forum for the international biomedical research community to compile their data on the genetic complexity of cancer in a unique resource. While this collection of articles cannot certainly claim completeness in any way, it represents an attractive collection of the different aspects of hormone-dependent cancers and will hopefully encourage further targeted research. SN - 9783036571164 SN - 9783036571171 KW - palbociclib KW - estrogen receptor KW - breast cancer KW - CDK4/6 KW - CDK4/6 inhibitors KW - therapy resistance KW - DNA repair KW - metabolic rewiring KW - quantitative proteomics KW - urothelial carcinoma KW - molecular subtypes KW - therapeutic target KW - prostate cancer KW - prognostic signature KW - diagnostic signature KW - biomarkers KW - cancer progression KW - aggressive cancer KW - androgen receptor KW - gene expression KW - insulin receptor KW - germline mutations KW - somatic mutations KW - PTEN KW - TMPRSS2 KW - ERG KW - androgen receptors KW - cervical cancer KW - alternative splicing KW - SR proteins KW - hnRNP KW - drug resistance KW - head and neck squamous cell carcinoma (HNSCC) KW - aberrant splicing events KW - human papillomavirus (HPV) infection KW - non-coding RNA (ncRNA) KW - methylation KW - mutational burden KW - next-generation digital histopathology KW - tissue cytometry KW - multiplexing KW - RNA ISH KW - cancer KW - tumor immune microenvironment KW - tumor microenvironment KW - IRX4 KW - transcript KW - isoforms KW - long non-coding RNA KW - single nucleotide polymorphisms KW - genome-wide association studies KW - thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general KW - thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ER -